1. Run X3:TC, load your savegame
2. Go to the Artificial Life setting menu ( [Esc] / Gameplay / Artificial Life)
3. Locate Pirate Guild 3: Dynamic AI and Guild System and set it to FALSE
4. Wait until the confirmation window appears
5. Save your game
6. Done !

Note: You can also delete all files related to Pirate Guild once you've uninstalled the plugin properly, simply run the “uninstall pirate guild” batch file located in you X3TC folder to do so.